Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  19
• Reference
  J:50327 Nomura H, et al., Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects. J Biol Chem. 1998 Oct 2;273(40):25967-73
• ID
  MGI:1331710

Genes

Gene	Assay Type	Description
Krd	visible phenotype
Pkd2l1	Southern analysis	PKDL cDNA

Notes

• Experiment
  In order to determine whether the mouse Pkdl gene is located within the Krd region deleted in C57BL/6J-Krd mice, (C57BL/6J-Krd x SPRET/Ei)F1 genomic DNA was analyzed with a human PKDL probe. The F1 mouse was found to have inherited hybridizing fragments contributed by the SPRET/Ei parent but not fragments from the wild type C57BL/6J or C3H (the strain in which the Krd deletion arose). The results indicated to authors that the Pkdl locus is within the region deleted by the Krd mutation.