Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  13
• Reference
  J:51890 Cox GA, et al., Identification of the mouse neuromuscular degeneration gene and mapping of a second site suppressor allele. Neuron. 1998 Dec;21(6):1327-37
• ID
  MGI:1333302

Genes

Gene	Assay Type
D13Mit215
Mnm	visible phenotype
D13Mit265
D13Mit177

Notes

• Experiment
  After a genome wide scam for loci modifying the, fifty-one (B6- +/nmd^2J x CAST/Ei)F2 and 16 +/nmd<2J (mnm^B/Mnm^C x Mnm^C/Mnm^C)N2 mildly affected progeny were finely genotyped for Chromosome 13 markers. Mnm was placed between D13Mit215 and D13Mit265. A positive modifier allele of Mnm was associated with the CAST/Ei strain (^C) and a negative modifer allele from C57BL/6J^B was identified. In addition a congenic strain B6.CAST-Mnm, was constructed and indicated that the genomic extent of Mnm included CAST/Ei derived markers D13Mit215 and D13Mit177.