Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  12
• Reference
  J:50525 Fijneman RJ, et al., High frequency of interactions between lung cancer susceptibility genes in the mouse: mapping of Sluc5 to Sluc14. Cancer Res. 1998 Nov 1;58(21):4794-8
• ID
  MGI:1335368

Genes

Gene
Sluc12
D12Nds2

Notes

• Experiment
  The fact that inbred O/20 was more susceptible to lung tumors then Congenic B10.O20 allowed for the mapping of lung tumor genes in OcB Recombinated Congenic strains. Lung tumor size and number could also be assesed by the QTL analysis of F2 mice derived from progenitor O/20 and various OcB strains. Analysis of F2 mice between O/20 and OcB-6 indicated a lung cancer susceptibility gene Sluc12 associated with mouse Chromosome 12 marker D12Nds2.