Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  4
• Reference
  J:43504 Sheldon M, et al., Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice [see comments]. Nature. 1997 Oct 16;389(6652):730-3
• ID
  MGI:1340248

Genes

Gene	Allele	Assay Type
D4Mit219		reported elsewhere
D4Mit155		reported elsewhere
Lepr		reported elsewhere
Iapls3-10		reported elsewhere
Dab1	Dab1^scm	visible phenotype
Ak4		reported elsewhere
D4Mit176		reported elsewhere
D4Mit304		reported elsewhere

Notes

• Experiment
  Authors analyzed YAC, BAC and P1 overlapping clones to physically map the scrambler phenotype region of mouse Chromosome 4. The Dab1 locus was identified as the gene associated with the scambler (scm) and yotari (yot) mutations through expression, directsequencing, and PCR analysis. The following order of loci was reported: D4Mit219 - D4Mit155 - Lepr - Iapls3-10 - Dab1^scm - Dab1^yot - Ak3 - D4Mit176 - D4Mit304. The iapls3-10 sequence is present in an intron of Dab1.