Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  17
• Reference
  J:56037 Shannon M, et al., Molecular characterization of Zfp54, a zinc-finger-containing gene that is deleted in the embryonic lethal mutation tw18. Mamm Genome. 1999 Jul;10(7):739-43
• ID
  MGI:1340375

Genes

Gene
Zfp51
Zfp40
Zfp54

Notes

• Experiment
  The complete coding sequence (AF080070) of the KRAB10 containing gene was sequenced . BLAST results indicated that the KRAB10 containing gene was similar to Clone 18 as reported in J:14373 Crossley PH, Proc Natl Acad Sci U S A 1991 Sep 15;88(18):7923-7. In the aforementioned Crossley reference Clone 18 mapped to the region of mouse Chromosome 17 deleated by t^w18. The authors here indicated that the KRAB10 containing gene genetically mapped to mouse Chromosome 17 and was tightly linked to Zfp51 and Zfp40, suggesting that the KRAB10 sequence is in fact Zfp54. The mapping of KRAB10 with mouse Chromosome 17 is in contrast with that reported in J:33558, Marine JC; etal. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.,Mamm Genome 1996 Jun;7(6):413-6, in which KRAB10 was identified as chromosome 9 marker Zfp76.