Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:52091 Alexander BJ, et al., Gene deletion explains both in vivo and in vitro generated chromosome 2 aberrations associated with murine myeloid leukemia. Leukemia. 1995 Dec;9(12):2009-15
• ID
  MGI:1342520

Genes

Gene	Assay Type
D2Mit159	SSLP
D2Mit126	SSLP
D2Mit241	SSLP
D2Mit3	SSLP
Tsp9	visible phenotype
D2Mit58	SSLP
D2Mit102	SSLP
D2Mit63	SSLP
D2Mit395	SSLP
D2Mit17	SSLP
D2Mit223	SSLP

Notes

• Experiment
  The authors used X-ray irradiated SJL/J or (SJL/J x CBA)F1 mice or virus infected cell lines as a model of murine myeloid leukemia. A majority of these mice contain Chromosome 2 aberrations. Since the breakpoints of the deletion are different, the authors propose the presence of tumor suppresor genes in the deleted region. Microsatellite mapping of the tumors narrowed the region to approximately a 6.5 cM interval between D2Mit126 and D2Miit395.