Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  17
• Reference
  J:56490 Kispert A, et al., The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr. Mamm Genome. 1999 Aug;10(8):794-802
• ID
  MGI:1342534

Genes

Gene	Assay Type
D17Leh66EI
Rps6ka2	overlapping clones, direct sequencing, Southern analysis
Smok1

Notes

• Experiment
  the authors used Southern hybridization with probes isolated from the Rps6ka2 cDNA and sequence data to map the Rps6ka2 gene to the D17Leh66EI region on mouse Chromosome 17. The Rps6ka2 gene covers at least 120-150kb of genomic DNA and consists of a minimun of 13 exons. The t-haplotype contains three Rps6ka2 loci, one in each of the D17Leh66a, D17Leh66b and D17Leh66c regions. With these studies, the authors have also narrowed the region containing the Tcr1 locus. The authors suggest that Tcr1 is most likely located 30kb upstream or 20kb downstream of the Rps6ka2 gene. However, the 20kb region between Tcp10b and the chromosomal breakpoint of t^h49 could not be excluded completely.