Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  14
• Reference
  J:39424 Ashman RB, et al., Evidence that two independent host genes influence the severity of tissue damage and susceptibility to acute pyelonephritis in murine systemic candidiasis. Microb Pathog. 1997 Mar;22(3):187-92
• ID
  MGI:1344590

Genes

Gene	Assay Type
Carg1	resistance/susceptibility

Notes

• Experiment
  The strain distribution patterns (SDPs) in 15 AKXL (AKR/J x C57L/J) RI strains suggest that at least two gene families facilitate the tissue damage caused by systemic infection of Candida albicans. One of these genes has been designated as Carg1. Carg1 has since been assigned to Chromosome 14. (J:52948, Ashman RB, Microb Pathog 1998 Dec;25(6):333-5)
  
  The parental strain AKR/J exhibits greater susceptibility to infection by C. albicans compared to parental strain C57L/J.