Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  10
• Reference
  J:52898 Roper RJ, et al., Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses. Endocrinology. 1999 Feb;140(2):556-61
• ID
  MGI:1346617

Genes

Gene	Assay Type
D10Mit180
Estq4	visible phenotype

Notes

• Experiment
  To understand the overall genetic control of estradiol regulated uterine response, the authors performed multiple trait analysis for both QTLs contributing to uterine weight and infiltrating eosinophils. Linkage was found to marker loci D4Mit6 (Estq1; LRT = 15.05), D5Mit296 (Estq2; LRT = 17.84), D10Mit180 (LRT = 16.02) and D11Mit67 (Estq3; LRT = 14.38; [a] = 0.10 and [a] = 0.05 thresholds equal 14.60 and 6.72, respectively). Based on the significance of D10Mit180 eosinophil infiltration, significant interaction of D10Mit180 in estradiol regulated responses, and the significance of the locus in mutilpe trait analysis, the QTL linked to D10Mit180 has been designated as Estq4.