Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  X
• Reference
  J:58685 Pretsch W, et al., X-linked glucose-6-phosphate dehydrogenase deficiency in Mus musculus. Biochem Genet. 1988 Feb;26(1-2):89-103
• ID
  MGI:1349583

Genes

Gene	Assay Type
G6pdx	enzyme activity

Notes

• Experiment
  A G6PD deficiency in mice was determined to be dependant on a gene on the mouse X chromosome. Two alleles were indicated; a wild type G6pdx ^a and a low activity allele G6pdx ^a-mlNeu . The X chromosome location was based to an extent on the fact that the low activity defect (G6pdx ^a-mlNeu) is expressed in hemizygous males and homozygous females , whereas females heterozygous for G6pdx ^a-mlNeu) exhibited partial enzyme activity.