Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:58152 Beamer WG, et al., Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome. 1999 Nov;10(11):1043-9
• ID
  MGI:1349586

Genes

Gene	Assay Type
D1Mit14	PCR amplified length variant
Bmd1	visible phenotype
D1Mit15	PCR amplified length variant
D1Mit17	PCR amplified length variant

Notes

• Experiment
  Bone mineral density (Bmd1) was measured as a quantitative trait (QTL) in a genome wide scan of 711 F2 mice in a genetic intercross involving C57BL/6J and CAST/Ei mice. C57BL/6J females express a low mineral bone density phenotype, alternatively CAST/Ei male express a high mineral bone density. Regression analysis was informative to show Bmd1 significantly associated with marker D1Mit15 within a defined QTL region bounded by markers D1Mit14 and D1Mit17. Due to the large size of the QTL region the authorsdid not suggest any candidate loci encoding for the bone mineral density phenotype.