Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  5
• Reference
  J:58152 Beamer WG, et al., Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome. 1999 Nov;10(11):1043-9
• ID
  MGI:1349587

Genes

Gene	Assay Type
D5Mit254	PCR amplified length variant
Bmd2	visible phenotype
D5Mit112	PCR amplified length variant
D5Mit89	PCR amplified length variant

Notes

• Experiment
  Bone mineral density (Bmd2) was measured as a quantitative trait (QTL) in a genome wide scan of 711 F2 mice in a genetic intercross involving C57BL/6J and CAST/Ei mice. C57BL/6J females express a low mineral bone density phenotype, alternatively CAST/Ei male express a high mineral bone density. Regression analysis was informative to show Bmp2 significantly associated with marker D5Mit112 within a defined QTL region bounded by markers D5Mit254 and D5Mit89. Due to the large size of the QTL region the authors did not suggest any candidate loci encoding for the Bone mineral density phenotype.