Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  13
• Reference
  J:58152 Beamer WG, et al., Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome. 1999 Nov;10(11):1043-9
• ID
  MGI:1349588

Genes

Gene	Assay Type
Bmd3	visible phenotype
D13Mit16	PCR amplified length variant
D13Mit15	PCR amplified length variant

Notes

• Experiment
  Bone mineral density (Bmd3) was measured as a quantitative trait (QTL) in a genome wide scan of 711 F2 mice in a genetic intercross involving C57BL/6J and CAST/Ei mice. C57BL/6J females express a low mineral bone density phenotype, alternatively CAST/Ei male express a high mineral bone density. Regression analysis was informative to show Bmd3 significantly associated with marker D13Mit16 within a defined QTL region bounded the centromere and D13Mit15. Due to the large size of the QTL region the authors did not suggest any candidate loci encoding for the Bone mineral density phenotype.