Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:60311 Brodnicki TC, et al., Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene. Immunogenetics. 2000 Jan;51(1):37-41
• ID
  MGI:1353454

Genes

Gene	Assay Type
D4Mit119
Idd11	resistance/susceptibility
D4Mit204
Slc9a1

Notes

• Experiment
  The authors generated three congenic strains to better define the Idd11 region on mouse Chromosome 4. Two of the strains had a significant decrease in the incidence of diabetes (P<0.001) compared NOD/Lt cntrol mice. The Idd11 locus was placed in a 13 cM interval between D4Mit119 and D4Mit204. The third congenic strain containing a B6 interval surronding the Slc9a1 locus was not protected against diabetes and eliminated the Slc9a1 as a candidate.