Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  2
• Reference
  J:59227 Horvat S, et al., Mapping of obesity QTLs in a cross between mouse lines divergently selected on fat content. Mamm Genome. 2000 Jan;11(1):2-7
• ID
  MGI:1353503

Genes

Gene	Assay Type
Fob1	visible phenotype

Notes

• Experiment
  Mice were selected for 53 generations for high and low fat content. High (F line) and Low (L line) mice were crossed creating F1 offspring that were mated to produce 436 F2 mice (233 females and 213 males). The F2 mice were genotyped for 71 MIT markers polymorphic in the progenitor strains to identify QTLs that contributed to the fat content phenotype. Fob1 as a QTL showed a significant peak LOD score of 4.0 at an approximate cM position of 45 on mouse Chromosome 2. Fob1 accounted for approximately 4.9 percent of the total fat variance across the F2 population explained by the QTL.