Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:58921 Matesic LE, et al., Mapping lipopolysaccharide response loci in mice using recombinant inbred and congenic strains. Genomics. 1999 Nov 15;62(1):34-41
• ID
  MGI:1353514

Genes

Gene	Assay Type
Fn1	reported elsewhere
D1Mit380	PCR amplified length variant
Mol2	visible phenotype
D1Mit215	PCR amplified length variant

Notes

• Experiment
  The difference in the response to LPS (lipopolysaccharide) exhibited between C57BL/6J and A/J mice allowed for the mapping of QTls in AXB/BXA Recombinant Inbred strains. Four provisional modifers of the LPS response were mapped to mouse Chromosomes 1, 7, 11,and 13. Mol2 was localized to a 10.9 cM region flanked by markers Fn1 and D1Mit215. Moreover congenic strain C.D2-VIL6 expresed the MOl2 phenotype within a donor region that included markers D1Mit380 and D1Mit215.