Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  X
• Reference
  J:58918 Warshawsky D, et al., Further examination of the Xist promoter-switch hypothesis in X inactivation: evidence against the existence and function of a P(0) promoter. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14424-9
• ID
  MGI:1354202

Genes

Gene	Assay Type
Rps12-ps1	PCR amplified length variant, direct sequencing
Rps19X-ps1
Xist

Notes

• Experiment
  While analyzing the presence of a promoter switch affecting Xist transcription, the authors determined that the P0 promoter was dispensable for XIST expression. However, Xist analysis of this region between 6.636kb and 6.136kb upstream of the Xist P1 promoter revealed homology to the Rps12 cDNA. Additional studies suggested that this was a processed pseudogene. The order/orientation of genes in the 7kb region upstream of Xist on the mouse X Chromosome was: 3' - Rps12-ps1 - 5' - 3' Rps19X-ps1 - 5' - 5' - Xist - 3'.