Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  6
• Reference
  J:61131 Lawson PR, et al., A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000 Mar;12(3):231-40
• ID
  MGI:1355534

Genes

Gene	Assay Type	Description
D6Mit24	Southern analysis
C1ra	Southern analysis	C1r-1f, C1r-1r
C1s1	Southern analysis	C1s-1f, C1s-1r
C3ar1	Southern analysis	C3ar1-1f, C3ar1-1r
D6Mit337

Notes

• Experiment
  The C1r, C1s and C3ar1 genes were mapped to Chromosome 6 on the EUCIB backcross with lod scores of 6.0, 9.7 and 7.12 respectively. C1r, C1s and C3ar1 co-segregated between the markers D6Mit24 and D6Mit337 at a position ~65 cM from the centromere. Fine scale mapping showed that the three genes co-segregate to a segment of DNA that spans ~0.17 cM.