Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  11
• Reference
  J:54529 Shinkura R, et al., Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet. 1999 May;22(1):74-7
• ID
  MGI:1858685

Genes

Gene	Allele	Assay Type
D11Mit331
Map3k14	Map3k14^aly	visible phenotype

Notes

• Experiment
  The authors mapped the aly locus between D11Mit331 and CA472-2 on mouse Chromosome 11 by analysis of polymorphic markers in recombinant mice generated by crossing aly/aly and MSM mice. Analysis of a 264kb physical map of the region resulted in the identification of the Map3k14 gene. Subsequent analysis and transgene complementation studies revealed that a point mutation in the Map3k14 gene was responsible for the aly phenotype.