Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:53794 Le Roy I, et al., Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping. Dev Psychobiol. 1999 Mar;34(2):139-58
• ID
  MGI:1858775

Genes

Gene	Assay Type
Start1	visible phenotype
D4Mit205
Start2	visible phenotype
D4Mit12

Notes

• Experiment
  Nineteen measures of sensorial, motor and body weight were subject to analysis in 389 female and male mice derived from reciprocal F1 and F2 mating of strains C57BL6/By and NZB/BlNJ . These traits were mapped via QTL analysis. In total 36 traits were mapped to chromosomes of which a number reached a threshold LOD score of 3.13 and were thus concidered significant. Two such QTL, startle response 1 (Start1) and startle response 2 (Start 2) mapped with mouse Chromosome 4 markers D4Mit205 ( LOD 3.87 ) and D4Mit12 (LOD 4.80) repectively. C57BL/6By-derived alleles confer earlier appearance of the startle response with a dominant mode of inheritance at Start1 and Start2.