Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  2
• Reference
  J:55766 Harper JM, et al., A locus on chromosome 2 influences the development of acute graft-versus-host disease in a murine model. Bone Marrow Transplant. 1999 Jun;23(11):1183-90
• ID
  MGI:1859959

Genes

Gene	Assay Type
Gvhd3	visible phenotype
D2Mit62	PCR amplified length variant

Notes

• Experiment
  A genome wide scan for markers that influence graft-versus-host disease was undertaken in (B10.D2 x DBA/2) X DBA/2 and (B10.D2 x DBA/2) X B10.D2 mice. The phenotype was determined by weight loss or death within 30 days of bone marrow transplantation. In 85 (B10.D2 x DBA/2) X B10.D2 a highly significant association of the weight loss phenotype with mouse Chromosome 2 marker D2Mit62 was observed, suggestive of a major QTL(Gvhd3) in this region.