Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:63757 Holan V, et al., A novel alloreactivity-controlling locus, Alan1, mapped to mouse chromosome 17. Immunogenetics. 2000 Jul;51(8-9):755-7
• ID
  MGI:1861673

Genes

Gene	Assay Type
D17Mit30
Alan1	immunological
D17Mit51
D17Mit19
D17Mit138

Notes

• Experiment
  Alan1 was initially identified using Recombinant Congenic strains CcS (STS/A x BALB/cHeA). Subsequent analysis of (CcS-5 x BALB/c) F2 hybrid mice was informative to map Alan1 with mouse Chromosome 17. This locus is responsible for the proliferative response to alloantigens in mixed lymphocyte cultures (MLC). Alan1 is independent of the H2 complex and showed a significant association with D17Mit30 and D17Mit51. The Range appears to be from D17Mit19 and D17Mit138.