Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  2
• Reference
  J:64907 Huang L, et al., The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency. Nat Genet. 1999 Nov;23(3):329-32
• ID
  MGI:1891843

Genes

Gene	Assay Type
Epb42
Bloc1s6	overlapping clones
D2Mit17
D2Mit30
D2Mit255
D2Mit396
D2Mit397
B2m

Notes

• Experiment
  The authors used information from genetic mapping to estimate the Stx13bp1^pa candidate region to be between Epb4.2 and B2m on Chromosome 2 in a 1 Mb interval. A YAC contig of the region was constructed using six overlapping YACs. YAC B4 (~530kb) carried the central portion of this interval. cDNA clones were identified using the YAC as a probe in a cDNA library. The authors were able to identify a cDNA showing reduced expression in pa mutant animals. Additional analysis revealed that mutations in this cDNA were responsible for the phenotype of Stx13bp1^pa mutant mice. The gene has been given the symbol Stx13bp1^pa (pallid).