Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  7
• Reference
  J:63552 Yatsuki H, et al., Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human. DNA Res. 2000 Jun 30;7(3):195-206
• ID
  MGI:1927109

Genes

Gene	Assay Type
Cars1	overlapping clones
Nap1l4	overlapping clones
Phlda2	overlapping clones
Slc22a18	overlapping clones
Cdkn1c	overlapping clones
Kcnq1	overlapping clones
Kcnq1ot1	overlapping clones
Trpm5	overlapping clones
Tssc4	overlapping clones
Cd81	overlapping clones

Notes

• Experiment
  The authors constructed a physical map of the mouse locus syntenic to the Beckwith-Wiedemann syndrome in humans. This region corresponds to the F4/F5 region on mouse Chromosome 7. BAC contigs between Nap1l4 and Cd81 were constructed and a 390kb region between Kcnq1 and Cd81 was sequenced. The order and orientation of markers in this region was determined to be centromere - 5' - Cd81 - 3' - 5' - Tssc4 - 3' - 3' - Trpm5 - 5' - 5' - Kcnq1 - 3' - Kcnq1ot1 - 5' - Kcnq1 - 3' - 3' - Cdkn1c - 5' - 5' - Slc22a1l-3' - 5' - Tssc3 - 3' - 3' - Nap1l4 - 5' - 3' - Cars - 5' - telomere. The Kcnq1ot1 transcript is between exon 11 and exon 9 of the Kcnq1 gene. This transcript extends at least 60kb from downstream to upstream of exon 10 in Kcnq1.