Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  2
• Reference
  J:64964 Cox GA, et al., The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development. Nat Genet. 2000 Oct;26(2):198-202
• ID
  MGI:1927526

Genes

Gene	Allele	Assay Type
D2Mit124
Fign	Fign^fi	visible phenotype
D2Mit326

Notes

• Experiment
  Authors fined mapped the fi mutation to a critical interval bounded by D2Mit326 and D2Mit124 after screening 2400 meiotic events in F2 progeny between STOCK-fidget and CAST/Ei. A YAC/BAC physical map of the region was constructed and a cDNA clone of interest was isolated. Mice with the f1 mutation had reduced levels of this mRNA. Subsequent analysis revealed a retro-transposon insertion into intron 2 of this gene that interfered with normal RNA processing. This gene was named fidgetin and given the symbol Fign.