Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  5
• Reference
  J:64725 Jun K, et al., Insertion of a retroviral solo long terminal repeat in mdr-3 locus disrupts mRNA splicing in mice. Mamm Genome. 2000 Oct;11(10):843-8
• ID
  MGI:1928150

Genes

Gene	Assay Type
Abcb1a	PCR amplified length variant, direct sequencing
Abcb1a	PCR amplified length variant

Notes

• Experiment
  The authors identified a phenotypic variation for mouse Chromosome 5 marker Abcb4 (alias mdr-3)in CF1 mutant mice versus the C57BL/6J wild type strain. Using PCR with sequencing strategies the authors attributed this mutation to an ecotropic viral insertion within intron 22 of Abcb4. The viral insertion is approximately 0.52 kb and leads to splicing variation in Abcb4.