Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  19
• Reference
  J:61295 Scimeca JC, et al., The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutants. Bone. 2000 Mar;26(3):207-13
• ID
  MGI:1928979

Genes

Gene	Allele	Assay Type
D19Mit32		PCR amplified length variant
D19Mit93		PCR amplified length variant
Tcirg1	Tcirg1^oc

Notes

• Experiment
  The localization of the oc (osteoscerotic) mutation to the pericentromeric region of mouse chromosome 19 was indicated in the genotypic analysis of 400 F2 mice in a (B6C3-a/a Atpi6i(oc)/+)F1 x Spretus) X (B6C3-a/a Atpi6i(oc)/+ X Spretus))F1 intercross. The analysis indicated that Atpi6i(oc) mapped to a region flanked by markers D19Mit32 and D19Mit93. Further analysis of 200 (B6C3-a/a Atpi6i(oc)/+) X (B6C3-a/a Atpi6i(oc)/+) F2 mice indicated that the Atpi6i(oc) mutation segregated with D19Mit68.