Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  1
• Reference
  J:67888 Graw J, et al., Ethylnitrosourea-induced mutation in mice leads to the expression of a novel protein in the eye and to dominant cataracts. Genetics. 2001 Mar;157(3):1313-20
• ID
  MGI:1932674

Genes

Gene	Allele	Assay Type
Cryge	Cryge^Aey1	visible phenotype

Notes

• Experiment
  Authors mapped the Aey1 mutation between D1Mit303 and D1Mit332. The small number of animals used in this cross and the resulting standard deviation presented both Cryba2 and six Cryg genes as candidates for the mutation. Sequence analysis revealed that amutation in Cryge destroys the first ATG of the protein. Further analysis suggests that a second ATG downstream whose phase is shifted by + 1 as compared to the Cryge ORF is used to make a protein in Aey1 mutant mice.