Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  1
• Reference
  J:68130 Kubota K, et al., Characterization of a surface membrane molecule expressed by natural killer cells in most inbred mouse strains: monoclonal antibody C9.1 identifies an allelic form of the 2B4 antigen. Immunology. 1999 Mar;96(3):491-7
• ID
  MGI:1932896

Genes

Gene	Assay Type	Description
Cd244a	molecular technique	C9.1
Akp1	isoelectric focusing

Notes

• Experiment
  The authors examined a correlation between C9.1 expression and Akp1 isozymein spleen cells from F2 progenies of (C57BL/6 x YNA)F1 mice. This strain combination was chosen because the C9.1(-) C57BL/6 mice carry the Akp1^a allele and the C9.1(+) YNA mice carry the Akp1^b allele.No recombination between the Akp1 and C9.1 gewne was observed indicating close linkage between the loci. Immunoprecipation analysis of the C9.1 antigen revealed that C9.1 was the Cd244 protein. The difference in molecular weights of the proteins was due to differential glycosylation of the protein backbones.