Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  9
• Reference
  J:68698 Kohara Y, et al., A major determinant quantitative-trait locus responsible for atopic dermatitis-like skin lesions in NC/Nga mice is located on Chromosome 9. Immunogenetics. 2001 Feb;53(1):15-21
• ID
  MGI:1933759

Genes

Gene	Assay Type
Derm1	visible phenotype
D9Mit163
D9Mit72
D9Mit143
D9Mit103
D9Mit207
Csk	reported elsewhere
D9Mit209

Notes

• Experiment
  Mouse strain NC/Nga is a model for human dermatitis. In an effort to map the gene or genes responsible for dermatitis in mice a genome wide scan was employed using 93 segregrants from a (NC/Nga x MSM/MS)F1 x NC backcross. Only backcross mice which exhibited severe dermatitis, were informative. A dermatitis locus (derm) significantly (chi square 16.4) segregated with markers D9Mit163, D9Mit72, D9Mit143, D9Mit103, D9Mit207 and D9Mit209 on mouse Chromosome 9. The authors suggest that Csk could be a candidate for the dermatitis phenotype in the NC/Nga strain. Authors used Derm1 for Derm.