Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  15
• Reference
  J:66987 Sugiyama F, et al., Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics. 2001 Jan 1;71(1):70-7
• ID
  MGI:1933795

Genes

Gene	Assay Type
Bpq6	visible phenotype
D15Mit152	PCR amplified length variant
Npr3	reported elsewhere

Notes

• Experiment
  C57BL/6J are sensitive to salt induced hypertension whereas A/J are non-salt-sensitive allowing for a genome wide scan for loci contributing to hypertension. 250 male mice from reciprocal backcrosses between (C57BL/6J x A/J)F1 x C57BL/6J were informativein mapping 6 Blood pressure QTLs to 5 mouse chromosomes. Beq6 interacted with Bpq5 and mapped with markers on mouse Chromosome 15. Bpq6 mapped with D15Mit152 with an F value of 19.8 and a P value of 0.0020. Suggested candidates for Bpq6 were Ptgerep2 andNpr3.