Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  10
• Reference
  J:68342 Horvat S, et al., Lack of socs2 expression causes the high-growth phenotype in mice. Genomics. 2001 Mar 1;72(2):209-12
• ID
  MGI:1934176

Genes

Gene	Allele	Assay Type
Socs2	Socs2^hg	direct sequencing

Notes

• Experiment
  The authors identified the Socs2 gene on the BAC 520L19 that was previously mapped to the deletion end-point in the hg region. Subsequent expression analysis revealed a lack of Socs2 mRNA in hg mice. Sequence analysis demonstrated a deletion breakpoint in intron 2 of the Socs2 gene that results in the complete loss of exon 3 and sequences downstream. This suggests a key role for the Socs2 gene in hg mice.