Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  10
• Reference
  J:69985 Wilson SM, et al., Mutations in Cdh23 Cause Nonsyndromic Hearing Loss in waltzer Mice. Genomics. 2001 Jun 1;74(2):228-33
• ID
  MGI:2136014

Genes

Gene	Assay Type
D10Mit138	overlapping clones, direct sequencing
Cdh23	overlapping clones, direct sequencing
D10Mit48	overlapping clones, direct sequencing
D10Mit29	overlapping clones, direct sequencing

Notes

• Experiment
  The authors constructed a physical map using the BACs 250C13 and 139F1 and an YAC 114C7. The minimum size of the interval was estimated to be 300kb between proximal D10Mit138 and distal markers D10Mit48 and D10Mit29. Mutational analysis of two waltzer alleles and expression analysis confirmed the role of the Cdh23 gene in the waltzer phenotype.