Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  13
• Reference
  J:69924 Benavides F, et al., The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene. Immunogenetics. 2001 Apr;53(3):233-42
• ID
  MGI:2136161

Genes

Gene	Allele	Assay Type
Ctsl	Ctsl^nkt	sequence analysis

Notes

• Experiment
  The authors identified a 118 bp deletion in the Ctsl gene of nkt/nkt mice. This results in the removal of the end of exon 6 and almost all of exon 7. Western analysis showed the absence of Ctsl indicating that nkt mutant mice lack stable Ctsl protein.