Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:58187 Turri MG, et al., High-resolution mapping of quantitative trait loci for emotionality in selected strains of mice. Mamm Genome. 1999 Nov;10(11):1098-101
• ID
  MGI:2150647

Genes

Gene	Assay Type
Emo1	visible phenotype
D1Mit452
D1Mit361
D1Mit113
D1Mit206
D1Mit355
D1Mit150

Notes

• Experiment
  Loci associated with emotionality on mouse chromosome 1 and mouse Chromosome 15 were further investigated using haplotype analysis with selected inbred DeFries strains H1, H2, L1, L2, C1, and C2 (H = high activity, L = low activity, C = control). Also, QTL analysis was performed using 71 (H1 X C1)F2 intercross animals. Animals were evaluated using open field activity (OFA) and open field defecation (OFD) tests as a measure of emotionality. Emotionality QTLs Emo1 and Emo2 were confirmed and localized to mouse Chromosome 1 between D1Mit452 and D1Mit361 (P = 0.0006 at approximately 73.9 cM - 87.0 cM) and mouse Chromosome 15 between D15Mit105 and D15Mit68 (P = 0.0038 at approximately 44.1 cM - 47.9 cM).