Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  15
• Reference
  J:43654 McClearn GE, et al., Genotypic selection provides experimental confirmation for an alcohol consumption quantitative trait locus in mouse. Mol Psychiatry. 1997 Oct-Nov;2(6):486-9
• ID
  MGI:2159394

Genes

Gene	Assay Type
Aaq1	visible phenotype
Tspo	reported elsewhere
D15Mit60
D15Mit144
D15Mit33
D15Bir1
D15Byu21
D15Mit3

Notes

• Experiment
  In the present study Aaq1, a QTL linked to alcohol acceptance that was previously mapped to a candidate region on mouse Chromosome 15 using BXD RI strains, was confirmed using a (C57BL/6J x DBA/2J)F2 population. Aaq1 mapped to 15 cM - 48 cM on mouse Chromosome 15 with a peak LOD score of 3.8 at approximately 30 cM. C57BL/6J-derived alleles confer increased alcohol acceptance in a dominant fashion at Aaq1. A potential candidate gene for Aaq1 is the peripheral benzodiazepine receptor gene, Bzrp.