Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  5
• Reference
  J:75144 Suzuki T, et al., Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene. Nat Genet. 2002 Mar;30(3):321-4
• ID
  MGI:2177746

Genes

Gene	Allele
Hps4	Hps4^le
D5Mit338
D5Mit314
D5Mit240
D5Mit316
D5Mit366
D5Mit117
D5Mit177
D5Mit317
D5Mit94
D5Mit24

Notes

• Experiment
  2,036 progeny from a (C57BL/6J-le/le X PWK)-le/+ females X C57BL/6J-le/le males were inforamtive to map the le mutation between distal markers D5Mit338 - D5Mit314 - D5Mit240 - D5Mit316 and proximally by marker D5Mit366. In the cross the Hps4^le mutationwas nonrcombinant with D5Mit117, D5Mit177, D5Mit317, D5Mit94, and D5Mit24. SNP analysis indicated that the le mutation was co-localized with Hps4.