Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  13
• Reference
  J:77538 Shimizu M, et al., A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density. Mamm Genome. 2002 Jul;13(7):335-40
• ID
  MGI:2385713

Genes

Gene
D13Mit303
Pbd2
Bmp6
D13Mit177

Notes

• Experiment
  The authors report the construction of a reciprocal congenic strain, P2.P6-Pbd2^a. Strains SAMP6 and SAMP2 were used as the donor and recipient strains, respectively. Whereas Pbd2 is a QTL locus defined by bone mass. The Congenic strain carries a SAMP6-derived mouse Chromosome 13 osteoporosis susceptible interval within the SAMP2-derived osteoporosis resistance background. The Interval could be defined as being contained within proximal marker D13Mit303 and distal marker D13Mit177. Within this region gene Bmp6 resides which is suggested as a candidate gene for Pbd2.