Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  9
• Reference
  J:78123 Kameya S, et al., Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6. Hum Mol Genet. 2002 Aug 1;11(16):1879-86
• ID
  MGI:2385959

Genes

Gene	Allele	Assay Type
D9Mit329
Mfrp	Mfrp^rd6
D9Mit23
82D20S		overlapping clones
Ptd009		overlapping clones

Notes

• Experiment
  A genetic cross was informative to fine map the Mfrp^rd6 region of mouse Chromosome 9. A Total of 657 F2 progeny using a (B6.C3Ga-rd6/rd6xCAST) F1 intercross were typed for flanking markers D9Mit329 and D9Mit23 Based on this cross the estimated genetic size for the chromosome 9 region containing Mfrp^rd6 was 0.46 +/- 0.19 cM (6 recombinants/1314 meiosis). In additon overlapping clones were used to refine the area to a distance of 0.15 +/- 11 cM as defined by flanking markers 821D20S and ptd009. This region contained mouse Mfrp which is considered a candidate for rd6.