Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  8
• Reference
  J:76508 Li X, et al., Genetic Dissection of Femur Breaking Strength in a Large Population (MRL/MpJxSJL/J) of F2 Mice: Single QTL Effects, Epistasis, and Pleiotropy. Genomics. 2002 May;79(5):734-40
• ID
  MGI:2386582

Genes

Gene	Assay Type
Fembrs2	visible phenotype
D8Mit125

Notes

• Experiment
  119 polymorphic markers were screened in 633 (MRL/MpJ x SJL/J)F2 female animals to detect loci associated with femur breaking strength. 7-week old female animals were used for the study. Fembrs2 was identified on mouse Chromosome 8 with LOD=4.3 at D8Mit125. SJL/J-derived alleles confer increased bone strength with dominant inheritance at Fembrs2.