Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• ID
  MGI:2386718

Genes

Gene	Assay Type
Tshp4	visible phenotype
D3Mit22

Notes

• Experiment
  76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. Tshp4, a QTL influencing tooth shape, mapped to mouse Chromosome 3. The Tshp4 interval is centered around 33.7 cM at D3Mit22. Tshp4 exceeds the P<0.001 significance threshold of LOD=4.185.