Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  11
• Reference
  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• ID
  MGI:2386720

Genes

Gene	Assay Type
Tshp9	visible phenotype
D11Mit62
Tshp10	visible phenotype
D11Mit15

Notes

• Experiment
  76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. Tshp9 and Tshp10, QTLs influencing tooth shape, mapped to mouse Chromosome 11. The Tshp9 interval is centered around 1.5 cM at D11Mit62 and the Tshp10 interval spans 28 cM - 40 cM on chromosome 11 near D11Mit15. Tshp9 and Tshp10 exceed the P<0.001 significance threshold of LOD=4.185.