Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  12
• Reference
  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• ID
  MGI:2386721

Genes

Gene	Assay Type
Tshp11	visible phenotype
D12Mit2
Tshp12	visible phenotype
D12Mit6

Notes

• Experiment
  76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. Tshp11 and Tshp12, QTLs influencing tooth shape, mapped to mouse Chromosome 12. The Tshp11 interval spans 1 cM - 19 cM and the Tshp12 interval spans 37 cM - 45 cM on chromosome 12. Tshp11 and Tshp12 exceed the P<0.001 significance threshold of LOD=4.185.