Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  11
• Reference
  J:82006 Johnson KR, et al., Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5. Genomics. 2003 Jan;81(1):6-14
• ID
  MGI:2653102

Genes

Gene
D11Mit224
D11Mit128
D11Mit214
Rhbdf2
D11Mit303
D11Mit48
D11Mit104
Grb2
Hgs

Notes

• Experiment
  The Cub mutation was mapped to 75 cM on mouse Chromosome 11. The cross used to map cub included a mutant mouse with a full curly coat (cub/cub Mcub/Mcub) mated with a CAST/ EiJ mouse and the resulting F1 hybrids (cub/+ Mcub/mcub) were then intercrossed. 280 meioses were analysed with the following results: standard errors (in parentheses). centromere - D11Mit224 - 5.5 cM (1.4) - D11Mit128 - 3.1 cM (1.0) - D11Mit214 - 2.6 cM (0.9) - cub - 1.8 cM (0.8) - D11Mit303 - 0.4 cM (0.4) - D11Mit48 - 1.7 cM (1.2)- D11Mit104.
  
  Potential candidate genes mapping near cub are Grb2 (75 cM) and Hgs (75 cM).