Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  8
• Reference
  J:82526 Morrison GM, et al., Signal Sequence Conservation and Mature Peptide Divergence Within Subgroups of the Murine beta-Defensin Gene Family. Mol Biol Evol. 2003 Mar;20(3):460-70
• ID
  MGI:2654226

Genes

Gene	Assay Type
Defb4	overlapping clones, sequence analysis
Defb6	overlapping clones, sequence analysis
Defb5	overlapping clones, sequence analysis
Defb3	overlapping clones, sequence analysis
Defb8	overlapping clones, sequence analysis
Defb7	overlapping clones, sequence analysis
Defb1	overlapping clones, sequence analysis
Defb2	overlapping clones, sequence analysis
Defb10	overlapping clones, sequence analysis
Defb9	overlapping clones, sequence analysis
Defb11	overlapping clones, sequence analysis
Defb15	overlapping clones, sequence analysis
Defb35	overlapping clones, sequence analysis
Defb13	overlapping clones, sequence analysis
Atp7b	overlapping clones, sequence analysis

Notes

• Experiment
  A series of BACs containing the beta-defensin gene family were identified and sequenced. The genes had previously shown to be in two clusters separated by 850 kb. Overall, the region containing the beta-defensin gene family on chromosome 8 was estimated to be 2.4 Mb. The order and orientation of the genes was shown to be: centromere - 5'-Defb4-3' - 5'-Defb6-3' - 5'-Defb5-3' - 5'-Defb3-3' - 3'-Defr1-5' - 5'-Defb7-3' - (850 kb) - (alpha-defensin cluster) - 5'-Defb1-3' - 5'-Defb2-3' - 5'-Defb1--3' - 3'-Defb9-5' - 3'-Defb11-5' - 3'-Defb15-5' - 5'-Defb35-3' - 5'-Defb13-3'.