Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:83220 Jackson AU, et al., Genetic polymorphisms in mouse genes regulating age-sensitive and age-stable T cell subsets. Genes Immun. 2003 Jan;4(1):30-9
• ID
  MGI:2661290

Genes

Gene	Assay Type
Cd8mts1	visible phenotype
D1Mit206	PCR amplified length variant
Cd8mts2	visible phenotype
D1Nds2	PCR amplified length variant

Notes

• Experiment
  Interval mapping was performed on a (BALB/c x C57BL/6)F1 x (C3H x DBA/2)F1 cross to identify QTLs affecting the level of T cell subsets in virgin and mated animals at 8 and 18 months of age. QTLs associated with CD8 memory T cell subset levels, Cd8mts1 and Cd8mts2, mapped to 95.8 cM (D1Mit206) and 59 cM (D1Nds2), respectively, on mouse Chromosome 1 with statistical significance of P<0.05. Cd8mts1 is associated with CD8 memory T cell levels in 8 month old virgin mice and 18 month old mated mice. Cd8mts2 is associated with CD8 memory T cell levels in 8 month old mated mice.