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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    4
  • Reference
    J:83220 Jackson AU, et al., Genetic polymorphisms in mouse genes regulating age-sensitive and age-stable T cell subsets. Genes Immun. 2003 Jan;4(1):30-9
  • ID
    MGI:2661294
Genes
GeneAlleleAssay TypeDescription
Cd4ts2 visible phenotype
D4Mit84 PCR amplified length variant
Cd4vts1 visible phenotype
D4Mit155 PCR amplified length variant
Notes
  • Experiment
    Interval mapping was performed on a (BALB/c x C57BL/6)F1 x (C3H x DBA/2)F1 cross to identify QTLs affecting the level of T cell subsets in virgin and mated animals at 8 and 18 months of age. A QTL associated with CD4 T cell subset levels, Cd4ts2, mapped to 37.7 cM (D4Mit84) on mouse Chromosome 4 and a QTL associated with CD4 virgin T cell subset levels, Cd4vts1, mapped to 49.3 cM (D4Mit155) on mouse Chromosome 4 with statistical significance of P<0.05. Cd4ts2 is associated with CD4 T cell levels in 8 month old mated mice. Cd4vts1 is associated with CD4 virgin T cell levels in 8 month old virgin mice.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory