Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:82238 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2003;
• ID
  MGI:2669310

Genes

Gene
nmf62
D2Mit407
D2Mit447
D2Mit94
Nmf220
Kcnq2
D2Mit148
D2Frk1
Kcnq2
D2Mit263
nmf88
nmf418
D2Mit83

Notes

• Experiment
  Linkage for nmf62 was established with D2Mit407 (LOD score 8.9) and D2Mit447 (LOD score 8.3) Order and distance between markers: D2Mit447 - 6.8 cM - nmf62 - 7.9 cM - D2Mit407
  The following mapping was provided for nmf220. D2Mit94 - 8.5 cM - Nmf220 - 5.9cM - D2Mit447; D2Mit94 LOD = 6.4; D2Mit447 LOD = 5.5
  
  The designated Nmf134 seizure phenotype was mapped as a binary dominant trait in 17 affected and 24 unaffected (C57BL/6J-Nmf134 x BALB/cByJ)F1 X BALB/cByJ N2 backcross mice. The apparent molecular interval was D2Mit148 - 2.5 cM - (Nmf134, D2Frk1=Kcnq2), with a peak LOD score of 4.2 at D2Frk1. Molecular Interval: D2Mit148 - 2.5 cM - (Nmf134, D2Frk1=Kcnq2).
  
  The following markers were ordered in Mouse Chromosome 2; The number between the loci represents the genetic distance: D2Mit263 - 16.8 cM - D2Mit148 - 2 cM - (nmf88, D2Frk1)
  
  Nmf418 was shown as mapping 8cM from D2Mit83 (LOD4.2); 20 cM from D2Mit94 (LOD1.9)