Mapping Data

Experiment

• Experiment
  TEXT-Congenic
• Chromosome
  1
• Reference
  J:85226 Shultz KL, et al., Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res. 2003 Feb;18(2):175-85
• ID
  MGI:2681007

Genes

Gene	Assay Type
Bmd19	visible phenotype
D1Mit282	PCR amplified length variant
D1Mit416	PCR amplified length variant
Bmd5	visible phenotype
D1Mit403	PCR amplified length variant
D1Mit194	PCR amplified length variant

Notes

• Experiment
  Congenic lines containing portions of the Bmd5 QTL region region were constructed using C3H/HeJ as the donor strain and C57BL/6J as the recipient strain. Analysis of congenic lines confirmed the effect of Bmd5 and narrowed the QTL region to between 73.2 cM (D1Mit194) and 100.0 cM (D1Mit403) on mouse Chromosome 1. A second nearby QTL with subtle effects was discovered between 36.9 cM (D1Mit282) and 64.5 cM (D1Mit416) and was named Bmd19.