Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  13
• Reference
  J:87283 Xu S, et al., An EM algorithm for mapping binary disease loci: application to fibrosarcoma in a four-way cross mouse family. Genet Res. 2003 Oct;82(2):127-38
• ID
  MGI:3036597

Genes

Gene	Assay Type
Fibrs3	resistance/susceptibility

Notes

• Experiment
  Linkage analysis was performed on 267 animals from a 4-way cross involving (BALB/c x C57BL/6)F1 x (C3H/He x DBA/2)F1 to identify QTLs associated with susceptibility to fibrosarcomas. 90 polymorphic loci were analyzed resulting in the detection of 3 fibrosarcoma-associated QTLs.
  
  Fibrs1 and Fibrs2 mapped to 11 cM (P=0.0117) and 92 cM (P=0.0186) on mouse Chromosome 4, respectively. Fibrs1 explains 34% of the phenotypic variance and Fibrs2 explains 27% of the phenotypic variance.
  
  Fibrs3 mapped to 24 cM on mouse Chromosome 13 and explains 26% of the phenotypic variance.